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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECH1
All Species:
16.36
Human Site:
S37
Identified Species:
40
UniProt:
Q13011
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13011
NP_001389.2
328
35816
S37
S
L
R
L
T
G
S
S
A
Q
E
E
A
S
G
Chimpanzee
Pan troglodytes
XP_001167817
328
35675
S37
S
L
R
L
T
G
S
S
A
Q
E
E
A
S
G
Rhesus Macaque
Macaca mulatta
XP_001084167
320
35031
S37
S
L
R
L
T
G
S
S
A
Q
E
E
A
P
D
Dog
Lupus familis
XP_533678
328
35870
A37
C
L
R
P
L
S
S
A
A
Q
D
E
A
S
T
Cat
Felis silvestris
Mouse
Mus musculus
O35459
327
36100
S37
S
L
R
S
L
S
S
S
A
Q
E
A
S
K
R
Rat
Rattus norvegicus
Q62651
327
36153
S37
S
L
R
S
L
S
S
S
A
Q
E
A
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086341
285
31456
A37
N
R
P
E
K
R
N
A
M
N
K
A
F
W
R
Zebra Danio
Brachydanio rerio
NP_001006068
308
33755
T37
E
S
T
P
A
F
T
T
L
S
I
S
Q
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608375
312
33800
T37
A
L
P
E
S
G
P
T
G
S
F
K
T
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784041
285
31394
M37
R
P
E
K
R
N
A
M
N
K
T
F
W
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
92.9
79.8
N.A.
74
75.3
N.A.
N.A.
N.A.
62.2
62.5
N.A.
48.1
N.A.
N.A.
51.2
Protein Similarity:
100
99.3
95.7
88.7
N.A.
87.8
87.8
N.A.
N.A.
N.A.
73.1
75
N.A.
65.5
N.A.
N.A.
65.8
P-Site Identity:
100
100
86.6
53.3
N.A.
53.3
53.3
N.A.
N.A.
N.A.
0
0
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
66.6
N.A.
60
60
N.A.
N.A.
N.A.
26.6
13.3
N.A.
40
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
10
20
60
0
0
30
40
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% D
% Glu:
10
0
10
20
0
0
0
0
0
0
50
40
0
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
10
10
10
0
0
% F
% Gly:
0
0
0
0
0
40
0
0
10
0
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
0
0
10
10
10
0
20
0
% K
% Leu:
0
70
0
30
30
0
0
0
10
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
10
10
0
10
10
0
0
0
0
0
% N
% Pro:
0
10
20
20
0
0
10
0
0
0
0
0
0
20
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
60
0
0
10
0
0
% Q
% Arg:
10
10
60
0
10
10
0
0
0
0
0
0
0
10
30
% R
% Ser:
50
10
0
20
10
30
60
50
0
20
0
10
20
30
0
% S
% Thr:
0
0
10
0
30
0
10
20
0
0
10
0
10
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _